Many people gain weight as they get older, even if they don’t eat more than usual and don’t cut back at the gym. How to explain this phenomenon ? New research carried out by the Karolinska Institutet in Sweden could shed light on this subject.
Fat is easily stored in fatty tissue with age
Researchers from Karolinska Institutet found that lipid turnover in adipose tissue decreases with age and thus facilitates weight gain even without changes in diet and sports habits.
To reach this conclusion, the researchers studied the fat cells of 54 men and women over an average period of 13 years. During this time, subjects – whether they gained or lost weight – exhibited decreased lipid turnover in adipose tissue. This lipid turnover corresponds to the rate at which lipids (or fat) are eliminated from fat cells.
This slowing down thus facilitates weight gain. In fact, the researchers noted that the weight of subjects who did not compensate for this deficit by eating fewer calories increased by 20% on average.
The regulation of our adipose tissue also affects our body mass
The researchers also looked at lipid shifting in 41 women who had bariatric surgery. As a result, only women who had a low rate of lipid reversal before surgery were able to maintain their weight loss.
Peter Arner, lead author of the study and professor in the Huddinge Department of Medicine at the Karolinska Institutet, said these results “indicate for the first time that the processes in our adipose tissue regulate changes in body weight during aging independently. other factors. This could open up new ways to treat obesity. ”
The best way to stay in shape is to exercise
Science Daily report that previous studies had already shown that the best way to accelerate the renewal of lipids in adipose tissue is to play sports. Researchers believe that surgeries aimed at weight loss would have better long-term results if they are combined with increased physical activity.
In any case, for Kristy Splading, author and principal researcher in the cell and molecular biology department of the Karolinska Institutet, “obesity and the diseases associated with it have become a global problem. Understanding the dynamics of lipids and what regulates body fat size in humans has never been more relevant. “